Open catalog · Healthcare commons · Early access

Machine-Actionable
Catalog for Healthcare

An open, curated registry of open-source healthcare software, AI models, clinical standards, datasets, and MCP servers — structured so humans and agents can both find and use them.

v0.1 early access  — entries are curated and trustworthy; automations and validations are Phase 2

Structured metadata

Every entry is
standards-compliant *

Each entry serializes against the right open metadata standard for its type, making the catalog queryable by software, reproducible in research, and ready for downstream portals.

Software CodeMeta 3.0
AI / ML models MLDCAT-AP 3.0
Datasets Croissant
MCP servers server.json
Catalog DCAT-AP
Data products Bitol ODPS
Standards / Specs schema.org + MACH

* Structured exports per standard are a Phase 2 implementation — entries are mapped to these standards in JSON-LD now; automated export generators and validators ship in Phase 2.

Taxonomy

7 entry types
across the commons

From clinical software to AI agents — every open healthcare artifact has a home here.

01Software
02AI / ML Models
03Datasets
04MCP Servers
05Data Sources
06Catalogs
07Specs

Catalog entries

Live entries,
growing with every commit

Every entry is a structured JSON-LD file in the repository. This list updates automatically on each push via CI. Contributions welcome via GitHub issues or the form below.

Total entries

203

Entry types

7/7

11089
Category
License
Catalogs

Health-RI Data Catalogue

Dutch national health research data catalogue built on the FAIR Data Point (FDP) specification. Metadata is described using HealthDCAT-AP, t…

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Catalogs

SPHN Metadata Catalog

Swiss national health research metadata catalog operated by the SIB Swiss Institute of Bioinformatics for the Swiss Personalized Health Netw…

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Data Sources

bio.tools

ELIXIR's registry of bioinformatics and life science software, hosting over 33,000 tools. Each entry is structured using biotoolsSchema and …

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Data Sources

NCBO BioPortal

The world's largest repository of biomedical ontologies and terminologies, maintained by the National Center for Biomedical Ontology (NCBO) …

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Data Sources

ChEMBL

Manually curated database of bioactive molecules with drug-like properties, maintained by EMBL-EBI. Integrates chemical, bioactivity, and ge…

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Data Sources

ClinicalTrials.gov

The world's largest public registry of clinical studies — 500,000+ registered trials covering interventional and observational studies, elig…

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Data Sources

ClinVar

Freely accessible public archive of human genomic variants classified for disease and drug response, maintained by NCBI/NLM/NIH. Contains 4.…

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Data Sources

CMS Medicare Coverage Database

The authoritative US federal database of Medicare coverage determinations — National Coverage Determinations (NCDs) and Local Coverage Deter…

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Data Sources

EMA Medicines Data

European Medicines Agency open data covering all EU-authorised medicines — approved and withdrawn applications, post-authorisation procedure…

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Data Sources

HealthMap

Automated global disease surveillance system developed at Boston Children's Hospital in 2006 by Clark Freifeld and John Brownstein. Aggregat…

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Data Sources

ICD-11 API

WHO REST API providing programmatic access to the ICD-11 Mortality and Morbidity Statistics (MMS) linearization — including entity lookups, …

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Data Sources

Open Targets Platform

Open science platform for systematic identification and prioritisation of drug targets using human genetic, genomic, and disease evidence. I…

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Data Sources

OpenAlex

Free, fully open academic knowledge graph covering 250M+ scholarly works, 250M+ authors, 100K+ institutions (with ROR IDs), and 30K+ journal…

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Data Sources

Scottish Health and Social Care Open Data

Open data platform managed by Public Health Scotland providing 104 health and social care datasets covering Scotland's NHS. Topics include e…

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Data Sources

openFDA

FDA public data API providing structured access to drug adverse event reports (FAERS), drug labeling, drug recalls, medical device adverse e…

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Data Sources

PAHO Open Data Portal

Open data portal of the Pan American Health Organization (PAHO), the WHO regional office for the Americas. Provides 140+ core health indicat…

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Data Sources

PhysioNet

Open repository of freely available physiological signals and related clinical data, maintained by the MIT Laboratory for Computational Phys…

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Data Sources

ProMED

Internet-based outbreak surveillance system launched in 1994 by the International Society for Infectious Diseases (ISID). Operated 24/7 by a…

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Data Sources

PubMed

The authoritative biomedical and life sciences literature index maintained by the US National Library of Medicine (NLM/NCBI). Covers 35M+ ci…

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Data Sources

Synapse

Open research data platform by Sage Bionetworks for storing, sharing, and collaborating on scientific data. Hosts DREAM Challenge datasets, …

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Data Sources

The Cancer Imaging Archive

Open repository of de-identified cancer imaging data funded by the National Cancer Institute (NCI) and hosted at the University of Arkansas …

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Data Sources

Vivli

Global clinical trial data sharing platform operated as an independent nonprofit. Hosts 8,000+ clinical trials representing 5.2 million part…

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Data Sources

WHO Disease Outbreak News

Official WHO publication series reporting confirmed and potential acute public health events of international concern across all hazards — i…

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Datasets

AgentClinic

Multimodal medical agent benchmark that simulates end-to-end clinical workflows. Presents AI agents with patient-facing dialogue, EHR record…

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Datasets

AmsterdamUMCdb

The first freely accessible European intensive care database. Contains de-identified clinical data from 23,106 ICU and high-dependency unit …

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Datasets

CAMELYON

Benchmark series for automated detection of breast cancer metastases in H&E-stained whole-slide images of sentinel lymph nodes — the first a…

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Datasets

Chi-Bench

Benchmark evaluating AI agents on end-to-end, long-horizon, policy-rich healthcare workflow automation. Covers three domains: provider prior…

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Datasets

EHRSHOT

Few-shot evaluation benchmark for EHR foundation models from the Shah Lab at Stanford Medicine. Contains 6,739 de-identified longitudinal pa…

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Datasets

eICU Collaborative Research Database

Multi-center ICU database containing data from 200,000+ admissions of 139,000+ patients across 335 ICU units at 208 hospitals across the con…

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Datasets

FHIR-AgentBench

Benchmark for evaluating LLM agent ability to retrieve and answer clinical questions from FHIR-structured EHR data. Contains approximately 3…

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Datasets

HealthBench

Physician-curated benchmark for evaluating large language models on realistic health conversations. Contains 5,000 multi-turn conversations …

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Datasets

MedAgentBench

FHIR-native benchmark for evaluating AI agents on real-world clinical tasks authored by practising physicians. Contains 300 tasks across 10 …

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Datasets

MedAlign

Clinician-curated benchmark for evaluating LLM instruction-following on real clinical tasks. Contains 983 natural-language instructions auth…

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Datasets

MedCalc-Bench

Benchmark dataset for evaluating LLM ability to perform clinical calculator tasks — a common but under-tested dimension of medical reasoning…

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Datasets

MedHELM

Comprehensive evaluation framework for benchmarking LLMs on medical tasks, built on Stanford CRFM's HELM platform. Covers 121 clinician-vali…

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Datasets

MetaboNet

The largest publicly available consolidated dataset for type 1 diabetes management. Aggregates 21 source datasets into a standardised schema…

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Datasets

MIMIC-IV

Large de-identified EHR dataset from 364,627 patients across 546,028 hospital admissions and 94,458 ICU stays at Beth Israel Deaconess Medic…

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Datasets

MLOmics Cancer Multi-Omics Benchmark

Standardised multi-omics benchmark dataset covering all 32 TCGA cancer types across four omics modalities: mRNA expression, microRNA, DNA me…

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Datasets

MoNuSeg

MICCAI 2018 grand challenge dataset for nucleus instance segmentation in H&E-stained histology images across multiple organs (breast, liver,…

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Datasets

NCI Imaging Data Commons

Cloud-native NCI cancer imaging platform providing programmatic access to 176 collections, 85,682 cases, 1,032,911 image series, and 99+ TB …

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Datasets

NCT-CRC-HE-100K

100,000 colour-normalised H&E image patches (224×224 px, 0.5 µm/px) from colorectal cancer and normal colon tissue across 9 tissue classes: …

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Datasets

NHS England Synthetic Clinical Notes

Synthetic clinical notes dataset generated by NHS England Data Science to support clinical NLP research and model development without exposi…

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Datasets

PANDA

The largest publicly available whole-slide imaging dataset, containing ~11,000 H&E-stained prostate biopsy WSIs with Gleason grading annotat…

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Datasets

PanNuke

Pan-cancer nucleus instance segmentation and classification dataset covering ~200,000 nuclei across 5 clinically important classes (neoplast…

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Datasets

PatchCamelyon

Binary image classification benchmark derived from CAMELYON16, consisting of 327,680 colour patches (96×96 px) extracted from H&E-stained ly…

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Datasets

PhysioNet Sepsis Challenge 2019

Benchmark dataset for early prediction of sepsis from hourly ICU clinical measurements, from the PhysioNet/Computing in Cardiology Challenge…

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Datasets

PTB-XL

Large publicly available 12-lead ECG dataset containing 21,799 clinical recordings from 18,869 patients (ages 0–95, 52% male) collected at t…

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Datasets

The Cancer Genome Atlas

Landmark cancer genomics program that comprehensively characterised the molecular landscape of 33 cancer types across 20,000+ primary tumour…

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Datasets

TUH EEG Corpus

The largest publicly available clinical EEG database, containing 60,000+ recordings from Temple University Hospital (2002–present) across 7 …

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MCP Servers

FHIR MCP Server (WSO2)

Exposes any FHIR R4/R5 server as an MCP server, enabling LLM agents to perform CRUD operations on FHIR resources through natural language vi…

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MCP Servers

OMCP

Model Context Protocol (MCP) server for the OMOP Common Data Model. Provides a structured, secure interface for LLM agents to query and anal…

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MCP Servers

openEHR Assistant MCP (Cadasto)

MCP server bridging AI assistants with openEHR design-time workflows. Exposes CKM archetype and template search, openEHR terminology concept…

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MCP Servers

openEHR MCP Server (deak-ai)

MCP server for runtime interaction with EHRbase via openEHR REST APIs. Exposes 11 MCP tools covering template operations, EHR lifecycle mana…

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MCP Servers

MCP SNOMED CT

Experimental MCP server exposing SNOMED CT concept lookup to LLM agents via any FHIR R4 terminology server. Enables AI agents to resolve cli…

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MCP Servers

ToolUniverse

Native MCP server exposing 211+ expert-curated biomedical tools to any MCP-compatible AI agent. Tools span drug discovery, therapeutic reaso…

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AI / ML Models

BioReason

Multimodal biological reasoning model fusing a DNA foundation model with a large language model to generate interpretable, step-by-step mech…

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AI / ML Models

CellViT

Vision Transformer-based framework for precise nucleus instance segmentation and classification in whole-slide histology images. U-Net encod…

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AI / ML Models

CONCH

Vision-language foundation model for histopathology pretrained on 1.17 million image-caption pairs from PubMed Central open-access articles …

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AI / ML Models

ECG-FM

Open foundation model for electrocardiogram (ECG) analysis with 90.9 million parameters built on the wav2vec 2.0 architecture. Pre-trained o…

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AI / ML Models

ECGFounder

Foundation model for electrocardiogram analysis pretrained on over 10 million ECG recordings. Evaluated across multiple clinical domains inc…

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AI / ML Models

EchoJEPA

Latent predictive foundation model for echocardiography trained on 18 million cardiac ultrasound images using joint-embedding predictive arc…

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AI / ML Models

ESM-2

State-of-the-art protein language model family from Meta AI, trained on 250 million protein sequences using masked language modelling. Avail…

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AI / ML Models

ESMC

State-of-the-art protein language model from EvolutionaryScale (Biohub) trained on ~2.8 billion protein sequences. Generates embeddings that…

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AI / ML Models

GeneAgent

Self-verifying LLM agent for gene-set analysis that autonomously queries domain databases (Gene Ontology, KEGG, NCBI Gene, PubMed) to annota…

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AI / ML Models

H-optimus-0

1.1-billion parameter vision transformer foundation model for histopathology — the largest publicly available pathology FM by parameter coun…

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AI / ML Models

HookNet

Multi-resolution convolutional neural network for semantic segmentation of whole-slide histopathology images. Uses two parallel U-Net-style …

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AI / ML Models

HoVer-Net

Simultaneous nucleus instance segmentation and classification model for H&E histology images. Uses horizontal and vertical distance maps (Ho…

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AI / ML Models

MedGemma

Google's family of Gemma 3 variants fine-tuned for medical text and image comprehension, released under the Health AI Developer Foundations …

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AI / ML Models

MedSAM

Universal medical image segmentation model adapting Meta's Segment Anything Model (SAM) to 30+ imaging modalities including CT, MRI, ultraso…

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AI / ML Models

MedSAM2

Extension of MedSAM to 3D volumetric medical imaging and video sequences, built on Meta's SAM2 architecture. Handles instance-level segmenta…

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AI / ML Models

nnDetection

Self-configuring framework for 3D volumetric medical object detection, applying the same automated configuration philosophy as nnU-Net to de…

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AI / ML Models

nnU-Net

Self-configuring framework for medical image segmentation that automatically adapts its architecture, preprocessing, training, and post-proc…

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AI / ML Models

OpenMed

Production-ready medical NLP toolkit providing state-of-the-art encoder transformers (BERT, ELECTRA, DeBERTa families) for biomedical named …

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AI / ML Models

OpenTSLM

Family of Time Series Language Models (TSLMs) from Stanford Biodesign for Digital Health (BDHG) that integrate time series as a native modal…

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AI / ML Models

PLIP

The first vision-language foundation model for computational pathology — a CLIP-based contrastive model fine-tuned on 208,414 pathology imag…

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AI / ML Models

Prov-GigaPath

Whole-slide pathology foundation model trained on real-world clinical data from Providence Health System — the first WSI-level foundation mo…

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AI / ML Models

scGPT

Generative foundation model for single-cell multi-omics analysis. Pre-trained on 33 million normal human cells from CellXGene across brain, …

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AI / ML Models

TotalSegmentator

Automated segmentation tool for 100+ anatomical structures in CT and MRI scans — covering abdominal organs (liver, spleen, pancreas, kidneys…

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AI / ML Models

TractSeg

Automated segmentation of 72 white matter fibre bundles from diffusion MRI tractograms, directly from raw peaks (fibre orientation distribut…

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AI / ML Models

TxAgent

LLM-based AI agent for therapeutic reasoning that orchestrates 211 biomedical tools spanning drug databases, genomic repositories, clinical …

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AI / ML Models

UNI

The largest pretrained vision foundation model for computational pathology — a ViT-L/16 encoder trained with DINOv2 self-supervised learning…

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AI / ML Models

UNI2-h

Successor to UNI — a ViT-H/14 vision foundation model for computational pathology from the Mahmood Lab at Harvard/BWH. 681M parameters, trai…

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AI / ML Models

Virchow

Self-supervised vision transformer (ViT-H/14, 632M parameters) pretrained on 1.5M whole-slide histopathology images from Memorial Sloan Kett…

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AI / ML Models

Virchow2

Second-generation Virchow pathology foundation model — ViT-H/14 (632M parameters) pretrained on 3.1M whole-slide images from Memorial Sloan …

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Software

3D Slicer

Free, open-source platform for medical image informatics, image processing, and three-dimensional visualisation. Supports segmentation, regi…

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Software

Android FHIR SDK

Google's open-source suite of Kotlin libraries for building offline-capable, mobile-first healthcare applications on Android using the HL7 F…

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Software

AndroidAPS

Open-source automated insulin delivery (AID) system for Android implementing the OpenAPS oref0/oref1 algorithm. Manages insulin pump communi…

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Software

batchgenerators

Framework-agnostic Python data augmentation library for 2D and 3D medical imaging. Provides spatial transforms (elastic deformations, rotati…

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Software

BBMRI-ERIC Negotiator

Open-source access negotiation platform for biobank and research infrastructure data requests. Manages the full Data Access Request (DAR) li…

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Software

Bio-Formats

Java library for reading and writing life sciences image file formats, developed by the Open Microscopy Environment (OME) consortium. Suppor…

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Software

Biomni

General-purpose biomedical AI agent framework from Stanford SNAP Lab. Combines LLM reasoning with retrieval-augmented planning and code exec…

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Software

Blaze

High-performance FHIR R4 server with an integrated CQL (Clinical Quality Language) evaluation engine, designed for population-wide aggregate…

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Software

CARE

FHIR R5-powered, modular open-source electronic health management information system (HMIS) developed by Open Healthcare Network Foundation …

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Software

CellProfiler

Open-source Python platform for automated quantitative measurement of biological phenotypes from microscopy images. Enables biologists witho…

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Software

Cornerstone3D

High-performance TypeScript framework for building web-based medical imaging applications, providing the rendering engine underlying the OHI…

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Software

Apache cTAKES

Open-source NLP platform for extracting clinical information from unstructured clinical text — radiology reports, discharge summaries, and E…

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Software

DataSHIELD

Infrastructure and R package suite enabling non-disclosive federated analysis of sensitive research data across distributed sites. Analysts …

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Software

dcm2niix

De facto standard tool for converting DICOM neuroimaging data to NIfTI format with BIDS-compliant JSON sidecars. Handles vendor-specific DIC…

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dcm4che

The de-facto open-source Java DICOM toolkit and library, providing a comprehensive implementation of the DICOM standard for medical imaging.…

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DCMTK

Reference C/C++ implementation of the DICOM standard — a comprehensive collection of libraries and command-line tools covering DICOM data en…

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DeepVariant

Deep learning-based DNA variant caller from Google Health. Processes aligned sequencing reads (BAM/CRAM), generates pileup image tensors, an…

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Software

DHIS2

The world's largest health management information system (HMIS) platform, deployed in over 80 countries and used by billions of people's hea…

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Digital Slide Archive

Web-based platform for managing, annotating, and running computational algorithms on large whole-slide and microscopy images. Supports image…

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DIRECT

PyTorch-based deep learning framework for accelerated MRI reconstruction from undersampled k-space data. Implements a range of state-of-the-…

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Discharge Documentation Generator

LLM-powered tool for generating draft clinical discharge letters from electronic health record notes. Synthesises medical notes from hospita…

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Drug Named Entity Recognition

Lightweight Python library for identifying drug and medication names in free text, with fuzzy matching for misspellings and integration with…

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EHRbase

Open-source openEHR Clinical Data Repository (CDR) providing a standard-based backend for interoperable clinical applications. Implements th…

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eva

Standardised evaluation framework for oncology foundation models, covering both pathology and radiology. Benchmarks patch-level, slide-level…

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FastSlide

High-performance C++20 library for reading whole slide images (WSI) in digital pathology, with first-class Python bindings. Thread-safe, AI/…

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FastSurfer

Deep learning neuroimaging pipeline for fast and accurate whole-brain MRI analysis. Performs whole-brain segmentation of 95+ cortical and su…

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FEMR

Python framework for large-scale self-supervised learning on electronic health records. Provides tooling for converting raw EHR data to the …

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Fiji

The standard batteries-included distribution of ImageJ for life sciences research. Bundles ImageJ with 200+ curated plugins covering segment…

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fMRIPrep

Robust and reproducible preprocessing pipeline for functional MRI (fMRI) data. Accepts BIDS-formatted input and performs brain extraction, s…

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GATK

The industry-standard toolkit for variant discovery in high-throughput sequencing data, developed by the Broad Institute. Implements best-pr…

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GNU Health

Libre hospital and health information system providing over 40 standard-based packages covering primary care, obstetrics, pediatrics, labora…

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Grand Challenge

Open-source Django/Docker platform for end-to-end development and deployment of medical imaging AI. Provides archives for managing DICOM dat…

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HAPI FHIR

The most widely used open-source Java implementation of the HL7 FHIR standard. Provides both a client library and a full JPA server with dat…

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HeuDiConv

Heuristic-driven DICOM-to-BIDS converter for neuroimaging. Converts raw DICOM acquisitions into BIDS-compliant datasets using customisable P…

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hf_ehr

HuggingFace-native framework for training large language models on structured electronic health records using the MEDS (Medical Event Data S…

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highdicom

High-level Python library built on pydicom for creating and reading derived DICOM objects — segmentations (SEG), parametric maps, structured…

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histolab

Python library for whole slide image (WSI) processing in computational pathology. Provides tissue detection, tiling, stain normalisation, an…

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HistomicsTK

Python toolkit for digital pathology image analysis providing colour normalisation, nuclei detection and segmentation, feature extraction, a…

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ilastik

Interactive machine learning toolkit for image segmentation, classification, object detection, counting, and tracking. Users interactively l…

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InVesalius

Open-source 3D medical image reconstruction software that generates volumetric models from 2D DICOM slices (CT and MRI). Features segmentati…

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ITK

Foundational open-source C++ toolkit for N-dimensional scientific image processing, with primary focus on medical imaging segmentation and r…

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ITK-SNAP

Widely used open-source application for interactive segmentation of 3D medical images — providing user-guided active contour and manual segm…

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Kaapana

Kubernetes-based open-source platform toolkit for building federated medical image analysis infrastructure. Orchestrates AI workflows (nnU-N…

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MedCAT

Clinical NLP toolkit for named entity recognition and linking in free-text clinical notes. Performs concept extraction and normalisation aga…

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Medplum

FHIR-native open-source developer platform for building and deploying clinical software, operated by Orangebot Inc. Provides a full-stack Ty…

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MedRAX

Agentic AI framework for chest X-ray (CXR) interpretation that dynamically orchestrates multiple specialist models — visual QA (CheXagent, L…

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MedRAX2

Updated iteration of the MedRAX agentic chest X-ray reasoning framework from the Bo Wang Lab. Extends the multi-model orchestration approach…

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Microsoft FHIR Server

.NET Core implementation of the HL7 FHIR standard maintained by Microsoft Healthcare. Supports FHIR R4 and R5 with pluggable persistence (SQ…

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MIRP

Python package for standardised medical image radiomics and preprocessing. Handles DICOM, NIfTI, and NRRD input, performs image preprocessin…

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Mirth Connect

The most widely used open-source healthcare integration engine — routes, transforms, and filters health messages between clinical systems ac…

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MITK

Open-source medical image computing toolkit combining a full-featured desktop workbench for visualization, segmentation, and registration wi…

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MOLGENIS EMX2

FAIR research data platform for building and managing biobank catalogues, rare-disease registries, and cohort data portals. Provides a flexi…

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MONAI Deploy

Framework for packaging, testing, and deploying medical AI applications into clinical production environments, part of the MONAI ecosystem. …

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MONAI Label

AI-assisted medical image annotation server with active learning. Runs as a lightweight server connecting to clinical viewers (3D Slicer, OH…

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MONAI Model Zoo

Curated repository of 30+ production-ready medical imaging models in standardised MONAI Bundle format, covering segmentation, detection, cla…

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MONAI

PyTorch-based open-source framework for deep learning in healthcare imaging, part of the PyTorch Ecosystem. Provides domain-specific transfo…

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MRIQC

Automated MRI quality control tool that extracts image quality metrics (IQMs) and generates visual reports for structural (T1w, T2w) and fun…

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napari

Fast, interactive, multi-dimensional image viewer for Python. The standard viewer for bio-imaging and computational pathology workflows — su…

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NeuroKit2

Python library for neurophysiological signal processing. Provides accessible, reproducible tools for ECG, EEG, EMG, EDA, and PPG signals — c…

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NiBabies

Specialised MRI preprocessing pipeline for human infant neuroimaging (0–2 years old), part of the NiPreps ecosystem. Handles the unique chal…

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Nightscout

Web platform for real-time continuous glucose monitoring (CGM) data broadcasting, storage, and visualisation. Acts as a personal diabetes da…

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NiiVue

Browser-based medical image visualisation library supporting 30+ neuroimaging formats including NIfTI, DICOM, MGH, NRRD, tractography, and s…

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nlmixr2

R package for nonlinear mixed-effects (NLME) modelling in pharmacometrics, designed to compete with commercial tools such as NONMEM and Mono…

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No-Show Prediction

Machine learning model for predicting patient no-shows at clinical appointments, actively deployed at UMC Utrecht. Identifies patients at hi…

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OHIF Viewers

Zero-footprint, web-based medical image viewer from the Open Health Imaging Foundation (OHIF). A configurable progressive web application wi…

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OMERO

Open-source platform for managing, visualising, and analysing microscopy image data. Supports 150+ imaging formats, centralised storage, web…

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Opal

Core database application for biobanks and epidemiological studies, developed under the OBiBa initiative (Maelstrom Research / McGill Univer…

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Open-ECG-Digitizer

Open-source tool for automatically extracting raw time-series voltage data from paper ECG images — scanned or photographed. Uses semantic se…

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OpenAPS

Community-built open-source reference implementation of an automated insulin delivery (AID) algorithm for Type 1 diabetes — the original DIY…

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OpenEMR

The most widely used open-source electronic health records (EHR) and medical practice management solution, governed by the OpenEMR Foundatio…

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OpenMRS

Open-source electronic medical records platform designed for resource-limited settings, deployed in 60+ countries across Africa, Asia, and L…

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OpenScribe

Open-source, local-first AI clinical scribe that records patient encounters and automatically generates structured clinical notes. Runs enti…

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OpenSlide

Low-level C library and Python bindings for reading whole-slide image (WSI) files across 11 proprietary vendor formats — including Aperio SV…

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Orthanc

Lightweight, open-source RESTful DICOM server for medical imaging, widely used in hospitals, research institutions, and imaging workflows. P…

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OSCAR McMaster

Canadian open-source electronic medical record system developed at McMaster University Department of Family Medicine, widely used by primary…

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Ozone HIS

Open-source Health Information System distribution that integrates OpenMRS 3 (EMR/clinical records), Odoo (ERP, billing, pharmacy), SENAITE …

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PathML

Open-source toolkit for computational pathology from Dana-Farber Cancer Institute. Covers the full digital pathology pipeline: whole slide i…

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Software

pydicom

The standard Python library for reading, modifying, and writing DICOM files. Used in virtually every Python-based medical imaging pipeline —…

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Software

PyHealth

Open-source Python toolkit for clinical deep learning that unifies datasets, tasks, and ML models across EHR, physiological signals, and med…

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Software

QuPath

Open-source desktop platform for digital pathology image analysis and bioimage informatics. Provides whole slide image (WSI) viewing, intera…

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Software

RDKit

Open-source cheminformatics toolkit for molecule manipulation, descriptor calculation, substructure searching, and pharmacophore analysis. T…

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Software

SimVascular

End-to-end open-source platform for patient-specific cardiovascular blood flow simulation. Provides a complete pipeline from medical image s…

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Software

SlicerIGT

3D Slicer extension providing a toolkit for image-guided interventions (IGT). Offers real-time instrument tracking, ultrasound and needle gu…

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Software

Slideflow

Unified deep learning framework for digital pathology, providing a consistent API across weakly supervised, strongly supervised, multiple in…

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Software

sMRIPrep

Structural MRI preprocessing pipeline from the NiPreps ecosystem. Performs skull stripping, tissue segmentation, and spatial normalisation a…

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Software

Spark FHIR Server

Open-source FHIR server built in C# by Firely and now maintained by Incendi. Supports FHIR R4 and STU3, available as NuGet packages or Docke…

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Software

Spezi

Open-source Swift framework for rapid development of modular, interoperable digital health applications on iOS and macOS. Provides reusable …

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Software

StarDist

Cell and nucleus instance segmentation library using star-convex polygon representations — predicts distances to object boundaries along fix…

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Software

STIR

Leading open-source library for PET and SPECT tomographic image reconstruction. Provides iterative and analytical reconstruction algorithms,…

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Software

dicom (suyashkumar)

High-performance Go library for reading, writing, and processing DICOM medical image files. Supports parsing of multi-frame imagery (encapsu…

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Software

SynthCity

Open-source Python library for generating and evaluating synthetic tabular data across multiple modalities — tabular, time series, survival …

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Software

Talk2Biomodels

AI agent framework for natural-language querying of systems biology models from the BioModels database (EMBL-EBI). Enables researchers to in…

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Software

TIA Toolbox

End-to-end Python API for computational pathology built on PyTorch, developed by the TIA Centre at the University of Warwick. Provides a uni…

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Software

Tidepool

Open-source nonprofit diabetes data platform that aggregates, visualises, and shares data from 50+ diabetes devices including CGMs (Dexcom, …

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Software

TorchIO

Open-source Python library for efficient loading, preprocessing, augmentation, and patch-based sampling of 3D medical images in deep learnin…

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Software

TrialGPT

End-to-end LLM framework for zero-shot patient-to-clinical-trial matching. Comprises three stages: retrieval (recalls 90%+ of relevant trial…

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Software

TRIDENT

Large-scale whole slide image processing toolkit from the Mahmood Lab at Harvard Medical School. Provides a single-command pipeline for tiss…

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vantage6

Privacy Enhancing Technology (PET) operations platform enabling federated learning and multi-party computation across distributed healthcare…

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Software

Veil

Open-source Chrome extension for real-time PII detection and redaction before submission to AI chat interfaces. Monitors text inputs and ide…

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Software

VistA

The Veterans Health Information Systems and Technology Architecture — the comprehensive EHR and HIS that has run the US Department of Vetera…

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Software

VolView

Open-source browser-based 3D radiological viewer for DICOM data with interactive cinematic volume rendering. All processing runs locally in …

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Software

Weasis

Comprehensive open-source DICOM viewer available as a desktop application and web-based deployment. Supports the full DICOM stack: 2D/3D ima…

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Software

WFDB Python

Native Python implementation of the Waveform Database (WFDB) standard for reading, writing, and processing physiological signal data. The pr…

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Software

WholeSlideData

Python library for patch sampling from whole-slide images (WSI) with annotation-aware batch iteration. Handles three tightly coupled tasks: …

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XNAT

Open-source biomedical imaging informatics platform developed by the Neuroinformatics Research Group (NRG) at Washington University School o…

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Specs

CDISC ADaM

The CDISC standard for analysis-ready clinical trial datasets — the layer between raw SDTM tabulation data and the statistical analyses subm…

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Specs

CDISC SDTM

The regulatory standard for organising and formatting clinical trial data submitted to the FDA and EMA. SDTM defines a set of domain models …

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Specs

DICOM

The international standard for transmitting, storing, retrieving, printing, processing, and displaying medical imaging information. Defines …

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Specs

FAIR Data Point (FDP) Specification

W3C Unofficial Proposal Draft specification for a metadata service that exposes digital objects following FAIR principles (Findable, Accessi…

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Specs

HL7 FHIR R4

The dominant healthcare interoperability standard, defining a RESTful API and JSON/XML resource formats for exchanging clinical and administ…

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HealthDCAT-AP

The official EU metadata specification for describing health datasets for secondary use, extending DCAT-AP 3.0 with health-domain semantics.…

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Specs

HITO

OWL ontology for systematically describing and classifying health IT application systems and software products. Defines classes and relation…

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Specs

International Patient Summary

A minimal, specialty-agnostic FHIR R4 Implementation Guide defining a structured electronic health record extract containing essential healt…

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Specs

ISO 13485:2016

The international quality management system (QMS) standard for organisations in the medical device lifecycle — design, production, storage, …

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Specs

ISO 14971:2019

The international standard for risk management of medical devices, including software as a medical device (SaMD) and AI/ML-enabled devices. …

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Specs

ISO 15189:2022

The international accreditation standard for medical laboratories, defining requirements for quality and competence in clinical testing. Cov…

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Specs

ODRL

W3C recommendation for expressing policies over data assets — permissions, prohibitions, and obligations. In healthcare, used to encode data…

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Specs

Open Nursing Core Implementation Guide

FHIR R4 implementation guide defining a standardised nursing data model covering the complete nursing process (ADPIE — Assessment, Diagnosis…

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Specs

openEHR

Open specification for a vendor-neutral EHR platform based on a two-level modelling paradigm — separating stable technical architecture from…

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Browse all entries on GitHub  ·  Contribute an entry

Open source in healthcare

Why open source matters

Open source enables transparency, reuse, and collaborative improvement. These principles matter everywhere, but are especially critical in healthcare, where the cost of opacity is borne by patients and health systems, not vendors.

UK Government · DSIT / GDS · 2026

AI, open code and vulnerability risk in the public sector

Recommends "open by default" even in an AI-accelerated threat landscape. Closing source does not remove vulnerabilities. It removes the external scrutiny that helps find and fix them.

Read guidance →

Ibrahim Haddad · LF AI & Data Foundation · 2026

Governing Our Digital Future: Every Government Needs an Open Source Program Office

Open source redistributes cost from vendor licensing to internal capability. Without deliberate governance, those costs accumulate as security and operational risk.

Read article →

How it works

Git-native,
issue-driven curation

All catalog data lives as JSON-LD files in the repository. Suggest an entry via a GitHub issue or the form below — curators handle the rest.

Step Action Who
01 Open an issue on GitHub or use the form below to suggest an entry Contributor
02 Fill in required fields and evidence links Contributor
03 CI validates JSON syntax, required fields, and duplicate identifiers — automated schema generation and validation planned for Phase 2 Automated
04 Curator reviews entry rationale and evidence quality Curator
05 Merge → site updated; structured exports (MLDCAT-AP, CodeMeta, Croissant, llms.txt) are Phase 2 automations Automated

We your support
and contributions!

Know a tool, model, or standard that should be here? Open an issue or suggest an entry below.

↗ Open an Issue on GitHub Suggest an entry below

Suggest an entry

Know a tool, model, dataset, or standard that belongs in MACH? Drop a link and a sentence — we will take it from there.

Thanks — we have received your suggestion and will review it. If you left an email we may follow up.

Browse the catalog on GitHub

All catalog data lives as open JSON-LD files in the repository. Watch for updates or read the contributing guide.

★ Star the repo if you find it useful — it helps others discover MACH.

↗ github.com/FORSE-H/MACH Contributing guide